The proposed research of developing GSGFET miniaturized flexible biosensor for allergen detection will greatly benefit the society. According to the Global Food Allergen Testing Market 2017-2021 report, a crucial driver in the market is the increasing allergic reactions among individuals. The improvement and development of allergen testing technology offers new opportunities for the new and current market players. This is leading to the growth of the global food allergen testing market. The deployment of various innovative techniques and equipment in food allergen testing techniques, significantly contributes to the growth of the global allergen testing market. There is a need to develop more efficient and reliable sensing technologies. Hence, we propose to develop state-of-the-art laser scribed graphene biosensor capable of allergen detection through an electrochemical impedance. We believe that this novel method will lead to real-time monitoring of allergen with high sensitivity and selectivity. Our research will address the critical challenges of surface functionalization of graphene via chemical modification and synthesize of the self-assembled monolayer of gold nanoparticle to achieve a reusable surface and the reduction of non-specific target binding. Gold particles will be conjugated with streptavidin and bounded to biotin-loaded aptamers. The gold nanoparticles function to enhance the signal by three folds compared to aptamers alone. The antigen-antibody (aptamers) reaction is then detected by the captured antibodies that are immobilized on the sensor surface.
Indra has recently completed a Master of Science in Nano electronic Engineering in Malaysia.
Veeradasan Perumal received his PhD in Nanoelectronic Engineering from Universiti Malaysia Perlis in 2014. During his study, he has successfully developed an innovative measurement tool as an approach for leptospirosis and cholera diagnosis. He fabricated and characterized a novel biosensor using combination of nanostructures and nanomaterials for rapid diagnosis of Leptospirosis and Vibrio cholera. He made an intriguing discovery that gene HAP1 from Leptospirosis can be extracted and immobilized onto gold nanoparticle associated nanomaterials surfaces without any surface modification. Next, he joined COINN at Universiti Teknologi PETRONAS as a postdoctoral researcher where he continuous his research in biosensor field. In COINN, he when to developed Tuberculosis diagnosis tools which have been filed for a patent. He later joined as a lecturer with Department of Mechanical Engineering in UTP. His current research interests are mainly on the synthesis and study of carbon-based nanomaterials such as graphene for flexible biosensor application.
Mohamed Shuaib Mohamed Saheed received his PhD in Electrical and Electronics from UTP in 2014. During his study, he focused on the synthesis of carbon nanotubes for the detection of gases using ionization principle. He later joined as a lecturer with Department of Fundamental and Applied Sciences in UTP, where he is currently a senior lecturer and became a member of COINN. His current research interests are mainly on the synthesis and study of carbon-based nanomaterials such as carbon nanotubes, graphene, and its hybrids for sensing and light emitting devices applications.
Norani Muti is a professor at the Department of Fundamental & Applied Sciences at Universiti Teknologi PETRONAS (UTP) and the fellow of the Academy of Sciences Malaysia (ASM). She founded “Centre of Innovative Nanostructures and Nanodevices (COINN)” with the objective of establishing a library of nanomaterials and synthesis techniques for accelerated production of innovative and beneficial commercialized products. In 2011, COINN has been recognized as NanoMalaysiaCOE based on its continuous R&D effort on nanotechnology, focusing on alternative and renewable energy. Research works undertaken are very much focused on cutting-edge research areas ranging from novel innovative nanostructures to functional nanodevices. She had secured more than RM25 million in research funding from various national grants and industrial petroleum research funding with accomplishment of more than 10 research grants as principle investigator.
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